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Novel evidence that the mannan-binding lectin pathway of complement activation plays a pivotal role in triggering mobilization of hematopoietic stem/progenitor cells by activation of both the complement and coagulation cascades.

作者信息

Adamiak M, Abdelbaset-Ismail A, Suszynska M, Abdel-Latif A, Ratajczak J, Ratajczak M Z

机构信息

Stem Cell Institute at James Graham Brown Cancer Center, University of Louisville, Louisville, KY, USA.

Department of Regenerative Medicine Warsaw Medical University, Warsaw, Poland.

出版信息

Leukemia. 2017 Jan;31(1):262-265. doi: 10.1038/leu.2016.278. Epub 2016 Oct 13.

DOI:10.1038/leu.2016.278
PMID:27733776
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5214582/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0952/5220127/da9ca50054bc/leu2016278f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0952/5220127/77ac90666418/leu2016278f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0952/5220127/da9ca50054bc/leu2016278f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0952/5220127/77ac90666418/leu2016278f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0952/5220127/da9ca50054bc/leu2016278f2.jpg

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Leukemia. 2016 Apr;30(4):919-28. doi: 10.1038/leu.2015.315. Epub 2015 Nov 19.
2
PAR1 signaling regulates the retention and recruitment of EPCR-expressing bone marrow hematopoietic stem cells.蛋白酶激活受体1（PAR1）信号传导调节表达内皮蛋白C受体（EPCR）的骨髓造血干细胞的保留和募集。
Nat Med. 2015 Nov;21(11):1307-17. doi: 10.1038/nm.3960. Epub 2015 Oct 12.
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Int J Mol Sci. 2023 Mar 2;24(5):4860. doi: 10.3390/ijms24054860.
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Tzu Chi Med J. 2021 Oct 21;34(3):270-275. doi: 10.4103/tcmj.tcmj_98_21. eCollection 2022 Jul-Sep.
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Psychopathology and Stem Cell Mobilization in Ultra-High Risk of Psychosis and First-Episode Psychosis Patients.精神病理学与超高危精神病和首发精神病患者的干细胞动员。
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