Attia Noura E
Department of Animal Medicine, Faculty of Veterinary Medicine, Zagazig University, Egypt.
Vet World. 2016 Sep;9(9):976-982. doi: 10.14202/vetworld.2016.976-982. Epub 2016 Sep 16.
This study was designed to evaluate the cardiac biomarkers and ultrasonography in prediction and early diagnosis of traumatic pericarditis (TP) in Egyptian buffaloes.
A total number of 47 buffaloes were included in the study and divided into two groups: Healthy (n=10) and diseased groups (n=37). Diseased buffaloes were admitted to the Veterinary Teaching Hospital at Zagazig University, Egypt, with a history of anorexia, sudden, and severe reduction of milk production with no response to a previous medical treatment some animals had edema at the dewlap and congestion of the jugulars. These animals were subjected to clinical examination, evaluation by hemato-biochemical analysis including cardiac biomarkers and sonography.
The hemato-biochemical analysis revealed leukocytosis with a shift to left and hyperfibrinogenemia (indicating inflammation). Serum cardiac biomarkers including cardiac troponin I (cTnI), cTnT, nitric oxide, creatine kinase myocardial band, and lactic dehydrogenase enzyme were significantly increased in buffaloes with TP compared with control ones. Ultrasonographically, there were hypoechoic materials with echogenic fibrin interspersed in between the pericardial sac.
The cardiac biomarkers may be considered a useful index in the early diagnosis of TP. Moreover, ultrasonography is an excellent tool for early prediction and diagnosis of such condition.
本研究旨在评估心脏生物标志物和超声检查在埃及水牛创伤性心包炎（TP）预测和早期诊断中的作用。
本研究共纳入47头水牛，分为两组：健康组（n = 10）和患病组（n = 37）。患病水牛被送往埃及扎加齐格大学兽医教学医院，有厌食、突然且严重的产奶量下降病史，先前治疗无反应，部分动物有垂皮水肿和颈静脉充血。对这些动物进行临床检查、血液生化分析（包括心脏生物标志物）评估及超声检查。
血液生化分析显示白细胞增多伴左移和高纤维蛋白原血症（提示炎症）。与对照组相比，患TP的水牛血清心脏生物标志物包括心肌肌钙蛋白I（cTnI）、cTnT、一氧化氮、肌酸激酶同工酶和乳酸脱氢酶显著升高。超声检查显示心包腔内有低回声物质，其间散布有回声性纤维蛋白。
心脏生物标志物可被视为TP早期诊断的有用指标。此外，超声检查是早期预测和诊断该病的极佳工具。
