Anaesthetic Department, Royal Perth Hospital, Perth, Western Australia, Australia.
Anaesthetic Department, University Hospitals of Coventry and Warwickshire NHS Trust, Coventry, UK.
Anaesthesia. 2016 Nov;71(11):1280-1283. doi: 10.1111/anae.13607.
Ten healthy volunteers received oxygen for 1 min, 2 min and 3 min at 10 l.min via a face mask, or humidified oxygen at 60 l.min via nasal prongs (Optiflow ) with the mouth closed and with the mouth open. The mean (SD) end-tidal oxygen partial pressure after 3 min face mask and Optiflow oxygenation, with mouth closed and open, were: 88.5 (6.2) kPa; 85.6 (6.4) kPa and 48.7 (26.4) kPa, respectively, p = 0.001. The equivalent mean (SD) transcutaneous oxygen partial pressures were: 34.6 (5.4) kPa; 36.4 (6.5) kPa and 25.5 (15.7) kPa, respectively, p = 0.03. High-flow humidified nasal oxygenation for 3 min with the mouth closed was as effective as 3 min face mask oxygenation.
10 名健康志愿者通过面罩以 10 l.min 的速度吸氧 1 分钟、2 分钟和 3 分钟，或通过鼻塞（Optiflow）以 60 l.min 的速度湿化吸氧，并闭唇和张口。3 分钟后面罩和 Optiflow 给氧，闭唇和张口时的平均（SD）呼气末氧分压分别为：88.5（6.2）kPa；85.6（6.4）kPa 和 48.7（26.4）kPa，p=0.001。等效平均（SD）经皮氧分压分别为：34.6（5.4）kPa；36.4（6.5）kPa 和 25.5（15.7）kPa，p=0.03。3 分钟闭唇高流量湿化鼻氧疗与 3 分钟面罩氧疗同样有效。
