高流量鼻导管给氧疗法治疗间质性肺炎急性加重：病例系列
High-flow nasal cannula oxygen therapy for acute exacerbation of interstitial pneumonia: A case series.
作者信息
Horio Yukihiro, Takihara Takahisa, Niimi Kyoko, Komatsu Masamichi, Sato Masako, Tanaka Jun, Takiguchi Hiroto, Tomomatsu Hiromi, Tomomatsu Katsuyoshi, Hayama Naoki, Oguma Tsuyoshi, Aoki Takuya, Urano Tetsuya, Takagi Atsushi, Asano Koichiro
机构信息
Division of Pulmonary Medicine, Department of Medicine, Tokai University School of Medicine, Kanagawa, Japan.
Division of General Medicine, Department of Medicine, Tokai University School of Medicine, Kanagawa, Japan.
出版信息
Respir Investig. 2016 Mar;54(2):125-9. doi: 10.1016/j.resinv.2015.09.005. Epub 2015 Nov 19.
We report 3 cases (all men, age: 69-81 years) of acute exacerbation of interstitial pneumonia (AEIP) that were successfully treated with a high-flow nasal cannula (HFNC), which delivers heated, humidified gas at a fraction of inspired oxygen (FIO2) up to 1.0 (100%). Oxygenation was insufficient under non-rebreathing face masks; however, the introduction of HFNC with an FIO2 of 0.7-1.0 (flow rate: 40 L/min) improved oxygenation and was well-tolerated until the partial pressure of oxygen in blood/FIO2 ratio increased (between 21 and 26 days). Thus, HFNC might be an effective and well-tolerated therapeutic addition to the management of AEIP.
我们报告了3例间质性肺炎急性加重（AEIP）病例（均为男性，年龄69 - 81岁），这些病例通过高流量鼻导管（HFNC）成功治疗。HFNC可输送加热、加湿的气体，吸入氧分数（FIO2）高达1.0（100%）。在使用非重复呼吸面罩时氧合不足；然而，引入FIO2为0.7 - 1.0（流速：40 L/min）的HFNC改善了氧合，并且在血液氧分压/FIO2比值升高之前（21至26天之间）耐受性良好。因此，HFNC可能是AEIP治疗中一种有效且耐受性良好的治疗辅助手段。
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