Cominetti Marco M D, Hughes David L, Matthews Susan E
School of Pharmacy, University of East Anglia, Norwich Research Park, Norwich, Norfolk NR4 7TJ, UK.
School of Chemistry, University of East Anglia, Norwich Research Park, Norwich, Norfolk NR4 7TJ, UK.
Org Biomol Chem. 2016 Nov 2;14(43):10161-10164. doi: 10.1039/c6ob02164f.
A new family of multivalent ligand platforms, the open-resorcinarenes, has been prepared in a straightforward two-step reaction. Modification of the core gives a range of topologically diverse scaffolds; functionalisation confirms the versatility of this approach, as shown through the formation of an octacalixarene array.
通过一个简单的两步反应制备了一类新的多价配体平台——开放型间苯二酚杯芳烃。对其核心进行修饰可得到一系列拓扑结构多样的支架;功能化证实了这种方法的通用性,八杯芳烃阵列的形成就证明了这一点。