Pawar Satyajit, Ganakumar Vanishri, Jha Saket, Ragesh R, Ray Animesh, Kakkar Aanchal, Sharma M C, Sharma S K
Department of Medicine.
Department of Pathology, All India Institute of Medical Sciences, New Delhi.
J Assoc Physicians India. 2016 May;64(5):66-68.
We report a case of pulmonary cryptococcoma, in an adult with recently detected diabetes, mimicking as lung cancer. A 45-year-old gentleman with past history of pulmonary tuberculosis presented with fever, cough with expectoration, pleuritic chest pain and hemoptysis. Chest radiograph and computed tomography revealed right lower lobe mass which significantly enhanced on contrast administration. Ultrasound guided biopsy was done which on histopathological examination showed non-necrotizing granulomas with narrow-based budding yeast cells suggestive of cryptococcosis. Detailed work-up for dissemination of infection was negative. A dramatic response to anti-fungal treatment was observed and the patient is doing fine on follow-up.
我们报告一例肺隐球菌瘤病例，患者为一名近期确诊糖尿病的成年人，其症状酷似肺癌。一名有肺结核病史的45岁男性，出现发热、咳痰咳嗽、胸膜炎性胸痛和咯血症状。胸部X光片和计算机断层扫描显示右下叶有肿块，增强扫描后显著强化。进行了超声引导下活检，组织病理学检查显示为非坏死性肉芽肿，伴有窄基芽生酵母细胞，提示为隐球菌病。针对感染播散的详细检查结果为阴性。观察到患者对抗真菌治疗反应显著，随访期间情况良好。
