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血糖控制不佳的糖尿病患者发生的腔内型肺隐球菌瘤

Intra-cavitary pulmonary cryptococcoma in poorly controlled diabetes mellitus.

作者信息

Kalyango Najibu, Kwizera Richard, Baluku Joseph B, Bongomin Felix

机构信息

Department of Medicine, College of Health Sciences, Makerere University, Kampala, P.o.Box, 7072, Uganda.

Infectious Diseases Institute, College of Health Sciences, Makerere University, Kampala, P.o.Box, 7072, Uganda.

出版信息

Med Mycol Case Rep. 2020 Feb 24;28:1-3. doi: 10.1016/j.mmcr.2020.02.005. eCollection 2020 Jun.

DOI:10.1016/j.mmcr.2020.02.005
PMID:32154097
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7056601/
Abstract

A 59-year-old HIV-negative Ugandan man presented with a long-standing history of respiratory symptoms and was found to have an intra-cavitary pulmonary cryptococoma by chest imaging and sputum culture. The serum cryptococcal antigen was negative. The sputum Xpert® MTB RIF Ultra assay was negative. He was previously treated for cavitary pulmonary tuberculosis. The patient had poorly controlled diabetes (HbA1c, 9.3%). The patient was successfully treated with oral fluconazole.

摘要

一名59岁的HIV阴性乌干达男子,有长期呼吸道症状病史,经胸部影像学检查和痰培养发现患有腔内肺隐球菌瘤。血清隐球菌抗原为阴性。痰Xpert® MTB RIF Ultra检测为阴性。他曾接受过空洞型肺结核治疗。该患者糖尿病控制不佳(糖化血红蛋白,9.3%)。该患者接受口服氟康唑治疗成功。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c752/7056601/d4d6187b368a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c752/7056601/dbad19bfd775/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c752/7056601/d4d6187b368a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c752/7056601/dbad19bfd775/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c752/7056601/d4d6187b368a/gr2.jpg

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本文引用的文献

1
[Imaging Findings of Pulmonary Cryptococcosis].[肺隐球菌病的影像学表现]
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2019 Dec 30;41(6):832-836. doi: 10.3881/j.issn.1000-503X.10985.
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An Unusual Case of Pulmonary Cryptococcus.一例罕见的肺隐球菌病病例
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Pulmonary Cryptococcoma Masquerading as Lung Cancer.伪装成肺癌的肺隐球菌瘤
J Assoc Physicians India. 2016 May;64(5):66-68.
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A Case of Pulmonary Cryptococcosis in an Immunocompetent Male Patient Diagnosed by a Percutaneous Supraclavicular Lymph Node Biopsy.1例免疫功能正常男性患者经皮锁骨上淋巴结活检诊断为肺隐球菌病
Tuberc Respir Dis (Seoul). 2015 Jul;78(3):276-80. doi: 10.4046/trd.2015.78.3.276. Epub 2015 Jun 30.
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Clinical features of pulmonary cryptococcosis in non-HIV patients in Japan.日本非HIV患者肺隐球菌病的临床特征
J Infect Chemother. 2015 Jan;21(1):23-30. doi: 10.1016/j.jiac.2014.08.025. Epub 2014 Oct 29.
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Treatment and outcomes among patients with Cryptococcus gattii infections in the United States Pacific Northwest.美国太平洋西北地区隐球菌感染患者的治疗和结局。
PLoS One. 2014 Feb 19;9(2):e88875. doi: 10.1371/journal.pone.0088875. eCollection 2014.
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Pulmonary cryptococcosis in non-AIDS patients.非艾滋病患者的肺部隐球菌病。
Braz J Infect Dis. 2012 Nov-Dec;16(6):531-9. doi: 10.1016/j.bjid.2012.07.004. Epub 2012 Nov 13.
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Clinical analysis of 76 patients pathologically diagnosed with pulmonary cryptococcosis.76 例肺部隐球菌病病理诊断的临床分析。
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