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儿童期泛发性金黄色葡萄球菌杀白细胞素阳性金黄色葡萄球菌感染:一例报告

Panton-Valentine leukocidin positive Staphylococcus aureus infection in childhood: a case report.

作者信息

Karlı Arzu, Belet Nurşen, Yanık Keramettin, Köken Özlem, Kılıç Mesut, Ceyhan Bilgici Meltem, Şensoy Gülnar

机构信息

Division of Pediatric Infectious Diseases, Department of Pediatrics, Ondokuz Mayis University Faculty of Medicine, Samsun, Turkey.

出版信息

Turk J Pediatr. 2015 Nov-Dec;57(6):615-617.

Abstract

Staphylococcus aureus is a common cause of musculoskeletal infections. Panton-Valentine leukocidin (PVL) is an exotoxin produced by S. aureus and is an important virulence factor. PVL-positive S. aureus infections have been associated with soft tissue infections and necrotizing pneumonia. In this case report, the clinical course of a 13-year-old boy who was admitted with right hip pain and fever, diagnosed with a gluteal abscess and incidentally discovered multiple cavitary pulmonary lesions, and had a methicillin susceptible and PVL-producing S. aureus (MSSA) extracted from the abscess culture is presented. The related literature is also reviewed.

摘要

金黄色葡萄球菌是肌肉骨骼感染的常见病因。杀白细胞素(PVL)是金黄色葡萄球菌产生的一种外毒素,是一种重要的毒力因子。PVL阳性的金黄色葡萄球菌感染与软组织感染和坏死性肺炎有关。在本病例报告中,介绍了一名13岁男孩的临床病程,该男孩因右髋疼痛和发热入院,被诊断为臀肌脓肿,并偶然发现多个肺空洞性病变,脓肿培养物中分离出一株对甲氧西林敏感且产PVL的金黄色葡萄球菌(MSSA)。同时也对相关文献进行了综述。

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