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头部和颈部的泛发性致死性金黄色葡萄球菌感染:病例系列及文献简要综述

Panton-Valentine leukocidin positive Staphylococcal aureus infections of the head and neck: case series and brief review of literature.

作者信息

Hanratty John, Changez Huma, Smith Andrew, Wales Craig

机构信息

Senior Clinical Fellow of Head and Neck Oncology, Department of Oral and Maxillofacial Surgery Department, Southern General Hospital, Glasgow, United Kingdom.

Specialist Registrar, Department of Microbiology, Southern General Hospital, Glasgow, United Kingdom.

出版信息

J Oral Maxillofac Surg. 2015 Apr;73(4):666-70. doi: 10.1016/j.joms.2014.10.004. Epub 2014 Oct 17.

DOI:10.1016/j.joms.2014.10.004
PMID:25544295
Abstract

Panton-valentine leukocidin (PVL) is a pore-forming cytotoxin produced by some clones of Staphylococcus aureus that is associated with infections ranging from uncomplicated skin and soft tissue infections to life-threatening necrotizing pneumonia. PVL S aureus-associated maxillofacial infections are rarely reported; therefore, a high degree of clinical suspicion is warranted and close liaison with microbiologists and appropriate samples are required for optimal management. This report discusses the management and learning points from 3 such cases managed by the Greater Glasgow and Clyde National Health Service maxillofacial surgical teams.

摘要

潘顿-瓦伦丁杀白细胞素(PVL)是由某些金黄色葡萄球菌克隆株产生的一种成孔细胞毒素,与从单纯性皮肤和软组织感染到危及生命的坏死性肺炎等各种感染有关。与PVL金黄色葡萄球菌相关的颌面部感染很少见报道;因此,需要高度的临床怀疑,与微生物学家密切联系,并需要采集适当的样本以进行最佳管理。本报告讨论了由大格拉斯哥和克莱德国民保健服务体系颌面部外科团队处理的3例此类病例的处理方法及经验教训。

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