Platonov S I, Burdak V N, Fedotov V P, Pogorelov V V
Vestn Dermatol Venerol. 1989(5):58-62.
Altogether 160 patients with early syphilis have been examined (49 ones with primary seropositive, 36 with secondary new, 75 with secondary relapsing condition). Abnormalities in the cerebrospinal fluid have been detected in 49 (30.6%) patients, of these Stage I-II abnormalities in 9, Stage II-III in 26, and Stage III-IV in 14 cases. Clinically the patients with abnormal liquor have developed multiple erosive and ulcerous chancres, papular eruptions on the palms and soles, copious papular rash, wide condylomas, alopecia, leukoderma; analyses have revealed marked dysproteinemia, impaired protein production, absorption-excretory and enzymic functions of the liver. The changes have been the most severe in the patients with the liquor abnormalities who abused alcohol.
共检查了160例早期梅毒患者（49例一期血清阳性，36例二期初发，75例二期复发）。49例（30.6%）患者脑脊液检测异常，其中9例为Ⅰ - Ⅱ期异常，26例为Ⅱ - Ⅲ期异常，14例为Ⅲ - Ⅳ期异常。临床上，脑脊液异常的患者出现了多发糜烂性和溃疡性溃疡、手掌和足底丘疹性皮疹、大量丘疹性皮疹、广泛的湿疣、脱发、白斑；分析显示有明显的蛋白血症、肝脏蛋白质生成、吸收排泄及酶功能受损。在滥用酒精的脑脊液异常患者中，这些变化最为严重。
