Department of Virology, National Institute of Public Health-National Institute of Hygiene, Warsaw, Poland.
J Med Virol. 2017 May;89(5):936-940. doi: 10.1002/jmv.24709. Epub 2016 Nov 9.
The aim of this study was to investigate the genetic variability of echovirus 6 (E6) isolates from environmental samples and clinical cases of aseptic meningitis from 2006 to 2014. The analysis of the VP1 region showed the extensive diversity (up to 18.8%) and revealed that E6 circulating in Poland belong to four groups. Environmental strains clustered in three groups excepting the 2012 outbreak group, which shows the sudden introduction of new epidemic variant with Asiatic origin. Data from the study established relationships of E6 from Poland with previously characterized strains and confirmed the importance of both clinical and environmental surveillance. J. Med. Virol. 89:936-940, 2017. © 2016 Wiley Periodicals, Inc.
本研究旨在调查肠病毒 6（E6）分离株的遗传变异性，这些分离株来自 2006 年至 2014 年的环境样本和无菌性脑膜炎临床病例。对 VP1 区的分析显示出广泛的多样性（高达 18.8%），并表明在波兰流行的 E6 属于四个组。除了 2012 年暴发组外，环境株聚集在三个组中，这表明具有亚洲起源的新流行变异株的突然出现。该研究的数据建立了波兰 E6 与先前特征化菌株的关系，并证实了临床和环境监测的重要性。J. Med. Virol. 89:936-940, 2017. © 2016 Wiley Periodicals, Inc.
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