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戊型肝炎的临床表现

Clinical Manifestations of Hepatitis E.

作者信息

Xin Shaojie, Xiao Long

机构信息

Liver Failure Treatment and Research Center, 302 Hospital, No.100 West 4th middle Road, Fengtai District, Beijing, 100039, China.

出版信息

Adv Exp Med Biol. 2016;948:175-189. doi: 10.1007/978-94-024-0942-0_10.

Abstract

The clinical manifestations of hepatitis E are similar to those of other types of viral hepatitis. While acute hepatitis E is usually self-limited, pregnant women and chronic liver disease patients suffering from acute hepatitis E usually present with severe clinical manifestations that may develop into fulminant hepatic failure. Chronic HEV infection is typically only seen in organ transplant patients; most HEV cases are asymptomatic and rarely display jaundice, fatigue, abdominal pain, fever, fatigue, or ascites. The clinical manifestations of HEV infection in neonates are diverse and have varied clinical signs, biochemistry, and virus biomarkers. Lastly, the extrahepatic manifestations and complications of hepatitis E are in need of further study.

摘要

戊型肝炎的临床表现与其他类型的病毒性肝炎相似。虽然急性戊型肝炎通常为自限性,但感染急性戊型肝炎的孕妇和慢性肝病患者通常会出现严重的临床表现,可能发展为暴发性肝衰竭。慢性戊型肝炎感染通常仅见于器官移植患者;大多数戊型肝炎病例无症状,很少出现黄疸、乏力、腹痛、发热、疲劳或腹水。新生儿戊型肝炎感染的临床表现多样,临床体征、生化指标和病毒生物标志物各不相同。最后,戊型肝炎的肝外表现和并发症有待进一步研究。

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