Dos Santos Pereira Rodrigo, Boos Fernanda Brasil, Gorla Luis Fernado, Garcia Idelmo Rangel, Okamoto Roberta, Hochuli-Vieira Eduardo
Int J Periodontics Restorative Dent. 2016 Nov/Dec;36(6):885-892. doi: 10.11607/prd.2404.
The aim of this study was to compare the bone resorption rate and histometry of ChronOS, a beta-tricalcium phosphate (β-TCP), mixed with autogenous bone grafts (1:1) with that of autogenous bone grafts alone in maxillary sinus elevation surgery. A total of 12 maxillary sinuses were grafted with an autogenous bone graft (control group) and 9 with ChronOS mixed with an autogenous bone graft (test group). Postoperative cone beam computed tomography (CBCT) was used to measure the initial graft volume after 15 days (T₁), and 6 months later another CBCT scan was performed to evaluate the final graft volume (T₂) and determine the graft resorption rate. The resorption outcomes were 45.7% ± 18.6% in the control group and 38.3% ± 16.6% in the test group (P = .17); the bone formation rate was 38.6% ± 10.5% in the control group and 25.4% ± 6.4% in the test group (P = .001). ChronOS mixed with autogenous bone graft demonstrated a resorption rate similar to that of the autogenous bone graft but with a difference in bone formation after 6 months.
本研究的目的是比较在鼻窦提升手术中,ChronOS(一种β-磷酸三钙(β-TCP))与自体骨移植材料按1:1混合后的骨吸收速率和组织计量学结果,与单纯使用自体骨移植材料的情况。总共12个上颌窦植入了自体骨移植材料(对照组),9个植入了ChronOS与自体骨移植材料的混合物(试验组)。术后使用锥形束计算机断层扫描(CBCT)测量15天后(T₁)的初始移植材料体积,6个月后进行另一次CBCT扫描,以评估最终移植材料体积(T₂)并确定移植材料的吸收速率。对照组的吸收结果为45.7%±18.6%,试验组为38.3%±16.6%(P = 0.17);对照组的骨形成率为38.6%±10.5%,试验组为25.4%±6.4%(P = 0.001)。ChronOS与自体骨移植材料混合后显示出与自体骨移植材料相似的吸收速率,但6个月后的骨形成情况有所不同。