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出血性中风的影像学检查

Imaging of Hemorrhagic Stroke.

作者信息

Hakimi Ryan, Garg Ankur

出版信息

Continuum (Minneap Minn). 2016 Oct;22(5, Neuroimaging):1424-1450. doi: 10.1212/CON.0000000000000377.

Abstract

PURPOSE OF REVIEW

Hemorrhagic stroke comprises approximately 15% to 20% of all strokes. This article provides readers with an understanding of the indications and significance of various neuroimaging techniques available for patients presenting with hemorrhagic strokes of distinct causes.

RECENT FINDINGS

The most common initial neuroimaging study is a noncontrast head CT, which allows for the identification of hemorrhage. Once an intracranial hemorrhage has been identified, the pattern of blood and the patient's medical history, neurologic examination, and laboratory studies lead the practitioner to pursue further neuroimaging studies to guide the medical, surgical, and interventional management. Given that hemorrhagic stroke constitutes a heterogeneous collection of diagnoses, the subsequent neuroimaging pathway necessary to better evaluate and care for these patients is variable based on the etiology.With an increasing incidence and prevalence of atrial fibrillation associated with the aging population and the introduction of three new direct factor Xa inhibitors and one direct thrombin inhibitor to complement vitamin K antagonists, oral anticoagulant use continues to increase. Patients on oral anticoagulants have a sevenfold to tenfold increased risk for intracerebral hemorrhage (ICH). Furthermore, patients who have an ICH associated with oral anticoagulant use have a higher mortality rate than those with primary ICH. Despite the reduced incidence of hypertension-related ICH over the past decade, it is expected that the incidence of ICH will continue to increase.

SUMMARY

Neuroimaging studies are integral to the identification of hemorrhagic stroke, determination of the underlying etiology, prevention of hematoma expansion, treatment of acute complications, and treatment of the underlying etiology, if indicated. Neuroimaging is essential for prognostication and thus directly impacts patient care.

摘要

综述目的

出血性卒中约占所有卒中的15%至20%。本文旨在让读者了解针对不同病因的出血性卒中患者可用的各种神经影像学技术的适应证及意义。

最新发现

最常见的初始神经影像学检查是头部非增强CT,可用于识别出血情况。一旦确诊颅内出血,血液分布模式以及患者的病史、神经系统检查和实验室检查结果会引导医生进一步进行神经影像学检查,以指导药物、手术及介入治疗。鉴于出血性卒中包含多种不同的诊断,后续为更好地评估和治疗这些患者所需的神经影像学检查路径会因病因不同而有所差异。随着人口老龄化,心房颤动的发病率和患病率不断上升,并且新引入了三种直接因子Xa抑制剂和一种直接凝血酶抑制剂来补充维生素K拮抗剂,口服抗凝剂的使用持续增加。服用口服抗凝剂的患者发生脑出血(ICH)的风险增加7至10倍。此外,与使用口服抗凝剂相关的ICH患者的死亡率高于原发性ICH患者。尽管过去十年高血压相关ICH的发病率有所下降,但预计ICH的发病率仍将继续上升。

总结

神经影像学检查对于识别出血性卒中、确定潜在病因、预防血肿扩大、治疗急性并发症以及在必要时治疗潜在病因至关重要。神经影像学对于预后评估必不可少,因此直接影响患者的治疗。

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