Rosahl S, Eßer D
Klinik für Neurochirurgie, HELIOS Klinikum, Nordhäuser Straße 74, 99089, Erfurt, Deutschland.
Klinik für Hals-, Nasen- und Ohrenheilkunde, Plastische Operationen, HELIOS Klinikum, Erfurt, Deutschland.
HNO. 2017 May;65(5):381-387. doi: 10.1007/s00106-016-0252-5.
The experience of the medical team, interdisciplinarity, quality of the physician-patient relationship, sensible use of modern technology, and a sound knowledge about the long-term results of observation and interventions all influence treatment quality in patients with vestibular schwannomas.
Compilation of findings regarding the results of observation and microsurgical treatment of patients with these tumors. Deduction of strategies for the medical management from these data.
Review of the pertinent literature concerning the course of the disease with observational management and microsurgical treatment with respect to tumor growth and symptoms.
Reported annual growth rates of vestibular schwannoma vary between 0.3 and 4.8 mm. Vertigo is the symptom that is most influential on quality of life regardless of the medical management strategy. Up to 75 % of patients are treated within 5 years of the primary diagnosis. Independent of the approach, reported resection rates are higher than 95 %, even with preservation of function as the primary goal. Recurrence rates after subtotal removal are three times higher than after complete removal. Facial nerve preservation is accomplished in more than 90 % of cases. With functional hearing before surgery and small tumors, the chance of hearing preservation exceeds 50 %.
Quality of life is primarily defined by symptoms caused by the tumor itself and only secondarily by the medical interventions. Treatment should be directed towards the preservation of the patient's quality of life from the beginning. Results of medical treatment should be superior to the natural course of the disease.
医疗团队的经验、多学科协作、医患关系质量、现代技术的合理应用以及对观察和干预长期结果的充分了解,都会影响前庭神经鞘瘤患者的治疗质量。
汇总有关这些肿瘤患者观察和显微外科治疗结果的研究发现。根据这些数据推导医疗管理策略。
回顾关于疾病进程的相关文献,涉及观察性管理以及肿瘤生长和症状方面的显微外科治疗。
报道的前庭神经鞘瘤年生长率在0.3至4.8毫米之间。无论采用何种医疗管理策略,眩晕都是对生活质量影响最大的症状。高达75%的患者在初次诊断后5年内接受治疗。无论采用何种手术入路,报道的切除率均高于95%,即使以保留功能为主要目标。次全切除后的复发率比完全切除后高三倍。超过90%的病例实现了面神经保留。术前有功能性听力且肿瘤较小的情况下,听力保留的几率超过50%。
生活质量主要由肿瘤本身引起的症状决定,其次才由医疗干预决定。治疗应从一开始就致力于保护患者的生活质量。医疗治疗的结果应优于疾病的自然进程。