Ridwan Sami, Urbach Horst, Greschus Susanne, von Hagen Johanna, Esche Jonas, Boström Azize
Department of Neurosurgery, University Hospital Bonn, Bonn, Germany.
Department of Radiology, University Hospital Bonn, Bonn, Germany.
World Neurosurg. 2017 Jan;97:495-500. doi: 10.1016/j.wneu.2016.09.123. Epub 2016 Oct 12.
Given the young age of onset and high probability of long-term disability after subarachnoid hemorrhage (SAH), the financial impact is expected to be substantial. Our primary objective was to highlight subsequent treatment costs after the acute in-hospital stay, including rehabilitation and home care, compared with costs for ischemic stroke.
The study included 101 patients (median age 52 years, 70 women) with aneurysmal SAH treated from July 2007 to April 2009. In-hospital costs were calculated using German diagnosis related groups. Rehabilitation costs depended on rehabilitation phase/grade and daily rate. Level of severity of care requirements determined the costs for home care.
Of patients, 54% received coiling and 46% received clipping. The clipping group included more poor-grade patients than the coiling group (P = 0.039); 23 patients died. Of 78 surviving patients, 70 received rehabilitation treatment (68 in Germany). Mean rehabilitation costs were €16,030 per patient. Patients in the clipping group generated higher rehabilitation costs and longer treatment periods in rehabilitation facilities (P = 0.001 for costs [€20,290 vs. €11,771] and P = 0.011 for duration (54.4 days vs. 40.5 days). Of surviving patients, 32% needed home care, of whom 52% required constant care. Multivariate regression analysis identified longer intensive care unit stay and poor Hunt and Hess grade as independent predictors of higher costs.
Aneurysmal SAH prevalently affects working individuals with long-term occupational disability necessitating long-term medical rehabilitation for most patients and subsequent nursing care in one third of survivors. Overall, SAH treatment generates far higher costs than reported for ischemic stroke.
鉴于蛛网膜下腔出血(SAH)发病年龄较轻且长期残疾的可能性较高,预计其经济影响巨大。我们的主要目标是突出急性住院期后的后续治疗费用,包括康复和家庭护理,并与缺血性中风的费用进行比较。
该研究纳入了2007年7月至2009年4月期间接受治疗的101例动脉瘤性SAH患者(中位年龄52岁,70例女性)。住院费用使用德国诊断相关组进行计算。康复费用取决于康复阶段/等级和每日费用率。护理需求的严重程度决定了家庭护理的费用。
54%的患者接受了血管内栓塞治疗,46%的患者接受了夹闭手术。夹闭手术组中病情较差的患者比血管内栓塞治疗组更多(P = 0.039);23例患者死亡。在78例存活患者中,70例接受了康复治疗(68例在德国)。平均每位患者的康复费用为16,030欧元。夹闭手术组患者产生的康复费用更高,在康复机构的治疗时间更长(费用方面P = 0.001[20,290欧元对11,771欧元],持续时间方面P = 0.011[54.4天对40.5天])。在存活患者中,32%需要家庭护理,其中52%需要持续护理。多因素回归分析确定重症监护病房住院时间延长和Hunt-Hess分级较差是费用较高的独立预测因素。
动脉瘤性SAH主要影响有工作能力的个体,导致长期职业残疾,大多数患者需要长期医学康复,三分之一的幸存者需要后续护理。总体而言,SAH的治疗费用远高于缺血性中风的报道费用。