Greiwe Justin, Bernstein Jonathan A
a Bernstein Allergy Group , Cincinnati , OH , USA.
b Department of Internal Medicine, Division of Immunology Rheumatology and Allergy , University of Cincinnati College of Medicine , Cincinnati , OH , USA.
Expert Rev Clin Immunol. 2017 Apr;13(4):311-318. doi: 10.1080/1744666X.2017.1249467. Epub 2016 Nov 3.
Chronic urticaria affects up to 1-3% of the general population and contributes to significant direct and indirect medical costs as well as decreased quality of life, which has a significant economic impact on our health care system. Areas covered: Given the prevalence of this condition on a large sector of the population, finding lasting relief for refractory cases is essential and is the focus of this review. Expert commentary: The choice of appropriate therapy in chronic refractory urticaria is not a 'one-size fits all' approach. Treatment should take multiple factors into consideration including the chronicity of hives, presence of physical urticaria, type of cellular infiltrate on skin histopathology, patient age, concomitant comorbid conditions, as well as patient preference and cost.
慢性荨麻疹影响着高达1%至3%的普通人群，导致了大量的直接和间接医疗费用以及生活质量下降，这对我们的医疗保健系统产生了重大的经济影响。涵盖领域：鉴于这种疾病在很大一部分人群中的患病率，为难治性病例找到持久的缓解方法至关重要，这也是本综述的重点。专家评论：在慢性难治性荨麻疹中选择合适的治疗方法并非“一刀切”的方式。治疗应考虑多种因素，包括荨麻疹的慢性程度、物理性荨麻疹的存在、皮肤组织病理学上细胞浸润的类型、患者年龄、伴随的合并症，以及患者的偏好和费用。
