Walter H, Nemeskéri J
Department of Human Biology/Physical Anthropology, University of Bremen, W. Germany.
Anthropol Anz. 1989 Jun;47(2):145-54.
A total of 675 individuals from the Hungarian isolate Ivád has been typed for 25 genetic polymorphisms. This sample was devided into three subgroups: 1. Full Ivádys (both spouses and their ancestors are members of the Ivád family; n = 330), 2. Half Ivádys (= either husband or wife and his or her, respectively, ancestors are from the Ivády family, the other partner from the outside population; n = 267), and 3. Non-Ivádys (married couples not belonging to the Ivády family; n = 78). The main concern of this paper is 1. to show to intra-Ivád variability of the distribution of various genetic parameters (allele frequencies, heterozygosity, gene diversity etc.) among these three groups, and 2. to analyze the impact of the different mating patterns of these groups on the genetic structure of the Ivád population. From the comparison of the Ivád gene frequencies with that of neighbouring populations (Pétervására and Erdökövesd) it is seen that drift or founder effects played some role. Within the Ivád population only few gene frequencies show a marked heterogeneity. As expected the average heterozygosity in Full Ivádys is somewhat lower than in Half Ivádys and Non-Ivádys, respectively. The pattern of genetic relationships of the various Ivád groups is in conformity with the demographic and historical facts of this village.
对来自匈牙利伊瓦德（Ivád）隔离群体的675人进行了25种基因多态性分型。该样本被分为三个亚组：1. 纯正伊瓦德人（夫妻双方及其祖先均为伊瓦德家族成员；n = 330），2. 半伊瓦德人（夫妻一方及其祖先来自伊瓦德家族，另一方来自外部群体；n = 267），3. 非伊瓦德人（不属于伊瓦德家族的已婚夫妇；n = 78）。本文主要关注的是：1. 展示这三组人群中各种基因参数（等位基因频率、杂合度、基因多样性等）在伊瓦德群体内部的分布差异；2. 分析这些群体不同交配模式对伊瓦德人群基因结构的影响。通过将伊瓦德基因频率与邻近群体（彼得瓦拉（Pétervására）和埃尔德克韦什德（Erdökövesd））的基因频率进行比较，可以看出遗传漂变或奠基者效应起到了一定作用。在伊瓦德人群中，只有少数基因频率显示出明显的异质性。正如预期的那样，纯正伊瓦德人的平均杂合度分别略低于半伊瓦德人和非伊瓦德人。伊瓦德各群体的遗传关系模式与这个村庄的人口统计学和历史事实相符。
