Roode G J, Bütow K-W, Naidoo S
Department of Anatomy and Department of Maxillo-Facial and Oral Surgery, University of Pretoria, P/Bag x 323, Arcadia 0007, South Africa.
Department of Maxillo-Facial and Oral Surgery, University of Pretoria, PO Box 1266, Pretoria 0001, South Africa; University of KwaZulu-Natal, Durban, South Africa; The Wilgers Hospital, Pretoria, South Africa.
Br J Oral Maxillofac Surg. 2017 Feb;55(2):127-131. doi: 10.1016/j.bjoms.2016.09.018. Epub 2016 Oct 10.
To identify the pathogenic micro-organisms that had colonised preoperatively in clefts in the soft palate and oro-nasopharynx, we retrospectively studied the preoperative microbiological profiles of 200 infants who had had primary repair of all types of cleft in the soft palate. Data from a private practice that specialises in the repair of facial clefts were extracted randomly from patients' files. We analysed the results of the culture of preoperative swabs taken from clefts in the soft palate and oro-nasopharynx, and the resistance profile of organisms towards various antibiotics. A total of 23 different pathogenic micro-organisms were isolated from 115 (57%) of the sample. Klebsiella pneumoniae most commonly colonised clefts in the lip, alveolus, and palate. This was considerably higher than in other groups. The second most common micro-organism was Staphylococcus aureus, which was found most often in patients with isolated clefts in the hard palate. Those with complete cleft lip and palate presented with more pathogenic micro-organisms in preoperative cultures than those with other types of cleft. We need to find a way to control pathogenic micro-organisms in the oral and oro-nasopharyngeal region preoperatively to limit postoperative complications.
为了确定术前定植于软腭和口鼻咽部裂隙中的致病微生物，我们回顾性研究了200例接受软腭各类裂隙一期修复手术的婴儿的术前微生物学特征。从一家专门从事面部裂隙修复的私人诊所的患者档案中随机提取数据。我们分析了取自软腭和口鼻咽部裂隙的术前拭子培养结果，以及微生物对各种抗生素的耐药情况。在115例（57%）样本中总共分离出23种不同的致病微生物。肺炎克雷伯菌最常定植于唇、牙槽突和腭部的裂隙中。这一比例显著高于其他组。第二常见的微生物是金黄色葡萄球菌，最常见于硬腭孤立性裂隙患者。与其他类型裂隙患者相比，完全性唇腭裂患者术前培养出的致病微生物更多。我们需要找到一种方法在术前控制口腔和口鼻咽部区域的致病微生物，以减少术后并发症。
