Kuchay Raja A H
School of Biosciences & Biotechnology, CBS, BGSB University.
Drug Discov Ther. 2017 Jan 15;10(6):292-299. doi: 10.5582/ddt.2016.01059. Epub 2016 Oct 17.
Administration of chemotherapy often leads to gastrointestinal mucositis (GIM). GIM manifests as nausea, abdominal pain and diarrhoea in recipients of chemotherapy. GIM is a major complication occurring in approximately 80% of patients receiving 5-flurouracil treatment. These side-effects may become so severe that significant dose reductions are required, ultimately affecting treatment efficacy and patient survival. Complementary and alternative medicine (CAM) is a growing area of public interest. This review will provide an overview of current knowledge of complementary medicinal therapies for chemotherapy induced GIM. An understanding of this evolving literature is useful in discussing these therapies with patients who are considering using them.
化疗给药常常会导致胃肠道黏膜炎（GIM）。在接受化疗的患者中，GIM表现为恶心、腹痛和腹泻。GIM是一种主要并发症，约80%接受5-氟尿嘧啶治疗的患者会出现。这些副作用可能会变得非常严重，以至于需要大幅减少剂量，最终影响治疗效果和患者生存率。补充和替代医学（CAM）是公众日益关注的领域。本综述将概述目前关于化疗诱导的GIM的补充药物治疗的知识。了解这一不断发展的文献对于与考虑使用这些疗法的患者讨论这些疗法很有帮助。
