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一名免疫性血小板减少性紫癜患者同时发生十二指肠弥漫性大B细胞淋巴瘤和回肠胃肠道间质瘤。

Synchronous Occurrence of Diffuse Large B-cell Lymphoma of the Duodenum and Gastrointestinal Stromal Tumor of the Ileum in a Patient with Immune Thrombocytopenic Purpura.

作者信息

Takahashi Tohru, Maruyama Yumiko, Saitoh Mayuko, Itoh Hideto, Yoshimoto Mitsuru, Tsujisaki Masayuki, Nakayama Masato

机构信息

Department of Hematology, Tenshi Hospital, Japan.

出版信息

Intern Med. 2016;55(20):2951-2956. doi: 10.2169/internalmedicine.55.6712. Epub 2016 Oct 15.

DOI:10.2169/internalmedicine.55.6712
PMID:27746431
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5109561/
Abstract

A 64 year-old woman with steroid-dependent immune thrombocytopenia developed anemia. Esophagogastroduodenoscopy revealed the presence of a tumor, which was diagnosed to be diffuse large B-cell lymphoma, in the second portion of the duodenum. F-fluorodeoxy glucose positron emission tomography showed an increased uptake mass in the pelvic cavity as well as in the duodenum. Though the duodenal tumor disappeared after 4 cycles of chemotherapy, the pelvic mass did not shrink in size. As a result, laparoscopic resection of the pelvic tumor was performed and the tumor was histologically diagnosed to be a gastrointestinal stromal tumor. Subsequently, the patient was treated with 2 more cycles of the chemotherapy. Eventually, thrombocytopenia completely resolved.

摘要

一名患有类固醇依赖型免疫性血小板减少症的64岁女性出现了贫血。食管胃十二指肠镜检查发现十二指肠第二部存在一个肿瘤,诊断为弥漫性大B细胞淋巴瘤。F-氟脱氧葡萄糖正电子发射断层扫描显示盆腔以及十二指肠有摄取增加的肿块。尽管经过4个周期的化疗后十二指肠肿瘤消失了,但盆腔肿块大小并未缩小。因此,对盆腔肿瘤进行了腹腔镜切除,组织学诊断该肿瘤为胃肠道间质瘤。随后,患者又接受了2个周期的化疗。最终,血小板减少症完全缓解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca56/5109561/08258e9f66df/1349-7235-55-2951-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca56/5109561/0fc2e1152911/1349-7235-55-2951-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca56/5109561/ca1006012e80/1349-7235-55-2951-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca56/5109561/7d5d5c280e37/1349-7235-55-2951-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca56/5109561/0076a57837a2/1349-7235-55-2951-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca56/5109561/8c937265c455/1349-7235-55-2951-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca56/5109561/08258e9f66df/1349-7235-55-2951-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca56/5109561/0fc2e1152911/1349-7235-55-2951-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca56/5109561/ca1006012e80/1349-7235-55-2951-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca56/5109561/7d5d5c280e37/1349-7235-55-2951-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca56/5109561/0076a57837a2/1349-7235-55-2951-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca56/5109561/8c937265c455/1349-7235-55-2951-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca56/5109561/08258e9f66df/1349-7235-55-2951-g006.jpg

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Cancer. 2015 Sep 1;121(17):2960-7. doi: 10.1002/cncr.29434. Epub 2015 Apr 30.
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结肠腺癌、弥漫性大B细胞淋巴瘤和骨髓增生异常综合征并存:一例报告。
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