Wolf S L, Minkwitz J A
Department of Rehabilitation Medicine, Emory University School of Medicine, Atlanta, GA 30322.
Arch Phys Med Rehabil. 1989 Sep;70(9):673-7.
This study determined whether the Achilles tendon reflex, H-reflex, and ankle range of motion (ROM) during ambulation undergo significant changes after application of benzocaine spray applied to the triceps surae skin area of eight stroke patients displaying spasticity in ankle plantar flexor muscles. The H-reflex amplitude increased significantly (p less than 0.05) at 30 minutes after both the benzocaine (0.346 +/- 0.101V) and the placebo (air spray, 0.324 +/- 0.078V) when the placebo was given first; however, there was no significant difference between the two interventions. A significant decrease in ankle ROM occurred during midswing at 20 (placebo administered first) and 30 (benzocaine administered first) minutes after the placebo, but this decrease was not significantly greater than the change after the benzocaine. Benzocaine spray did not change motor neuron excitability level or improve the subject's ability to perform a functional task.
本研究确定了,在对8名踝关节跖屈肌表现出痉挛的中风患者的小腿三头肌皮肤区域喷洒苯佐卡因后,步行过程中的跟腱反射、H反射和踝关节活动范围(ROM)是否会发生显著变化。当先给予安慰剂(空气喷雾)时,苯佐卡因(0.346±0.101V)和安慰剂(空气喷雾,0.324±0.078V)给药后30分钟,H反射波幅均显著增加(p小于0.05);然而,两种干预措施之间没有显著差异。安慰剂给药后20分钟(先给予安慰剂)和30分钟(先给予苯佐卡因)时,摆动中期踝关节ROM显著降低,但这种降低并不比苯佐卡因给药后的变化显著更大。苯佐卡因喷雾并未改变运动神经元兴奋性水平,也未改善受试者执行功能性任务的能力。