Jacobson D M, Corbett J J
Department of Neurology, Marshfield Clinic, WI 54449.
Arch Neurol. 1989 Sep;46(9):1005-8. doi: 10.1001/archneur.1989.00520450075023.
We reviewed the case records and radiographic studies of 41 patients with primary position downbeat nystagmus seen during a 5-year period to investigate whether a relationship existed between dolichoectasia of the vertebrobasilar artery and cases of unknown cause. The cause of downbeat nystagmus could not be determined in 12 cases (29%). Two of these cases had dolichoectasia of the vertebrobasilar artery as the only identifiable abnormality. One other case had a dolichoectatic vertebrobasilar artery, but other potential etiologic factors for the development of downbeat nystagmus were present. Compression of the caudal brain stem by an enlarged and tortuous vertebrobasilar arterial system may be the cause of downbeat nystagmus in some cases unassociated with more commonly recognized causes.
我们回顾了5年间41例原发性下跳性眼球震颤患者的病例记录和影像学研究，以调查椎基底动脉扩张迂曲与不明原因病例之间是否存在关联。12例（29%）患者的下跳性眼球震颤病因无法确定。其中2例仅发现椎基底动脉扩张迂曲这一异常。另有1例存在扩张迂曲的椎基底动脉，但也有其他可能导致下跳性眼球震颤的病因。在一些与更常见病因无关的病例中，扩大迂曲的椎基底动脉系统对延髓的压迫可能是下跳性眼球震颤的病因。
