Donnell C D, McNally R J
Behav Res Ther. 1989;27(4):325-32. doi: 10.1016/0005-7967(89)90002-8.
In this study, we examined the effects of anxiety sensitivity on the response to hyperventilation in college students with and without a history of spontaneous panic attacks. Reiss et al.'s (Behav. Res. Ther. 24, 1-8, 1986) Anxiety Sensitivity Index and Norton et al.'s (Behav. Ther. 17, 239-252, 1986) Panic Attack Questionnaire were used to select Ss. Following five min of voluntary hyperventilation, high anxiety sensitivity Ss reported more anxiety and more hyperventilation sensations than did low anxiety sensitivity Ss. A history of panic was only associated with enhanced responding to hyperventilation in Ss with high anxiety sensitivity; low anxiety sensitivity Ss who had experience with panic were no more responsive than low anxiety sensitivity Ss who had never had a panic attack. These findings suggest that high anxiety sensitivity may be a crucial determinant of panic attacks provoked by biological challenges (e.g. hyperventilation, sodium lactate infusion).
在本研究中，我们考察了焦虑敏感性对有或无自发性惊恐发作史的大学生对过度通气反应的影响。采用赖斯等人（《行为研究与治疗》，第24卷，第1 - 8页，1986年）的焦虑敏感性指数和诺顿等人（《行为治疗》，第17卷，第239 - 252页，1986年）的惊恐发作问卷来选择研究对象。在进行五分钟的自主过度通气后，高焦虑敏感性的研究对象比低焦虑敏感性的研究对象报告了更多的焦虑和更多的过度通气感觉。惊恐发作史仅与高焦虑敏感性研究对象对过度通气的反应增强有关；有过惊恐发作经历的低焦虑敏感性研究对象与从未有过惊恐发作的低焦虑敏感性研究对象相比，反应并无差异。这些发现表明，高焦虑敏感性可能是由生物学挑战（如过度通气、输注乳酸钠）引发惊恐发作的关键决定因素。
