无细胞miRNA-141和miRNA-205作为前列腺癌生物标志物
Cell-Free miRNA-141 and miRNA-205 as Prostate Cancer Biomarkers.
作者信息
Osipov Ivan D, Zaporozhchenko Ivan A, Bondar Anna A, Zaripov Marat M, Voytsitskiy Vladimir E, Vlassov Valentin V, Laktionov Pavel P, Morozkin Evgeny S
机构信息
Novosibirsk State University, Novosibirsk, Russia.
Institute of Chemical Biology and Fundamental Medicine SB RAS, Novosibirsk, Russia.
出版信息
Adv Exp Med Biol. 2016;924:9-12. doi: 10.1007/978-3-319-42044-8_2.
Expression levels of five miRNAs (miR-19b, miR-21, miR-126, miR-141, miR-205) were measured in the plasma of healthy donors and prostate cancer patients. It was shown that miR-141 expression level efficiently discriminates early stage prostate cancer patients and correlates with the Gleason score.
在健康供体和前列腺癌患者的血浆中检测了五种微小RNA（miR-19b、miR-21、miR-126、miR-141、miR-205）的表达水平。结果显示，miR-141的表达水平能够有效区分早期前列腺癌患者，并且与 Gleason评分相关。
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