McDonald J L, Schemehorn B R, Stookey G K
J Dent Res. 1978 Feb;57(2):345-8. doi: 10.1177/00220345780570023401.
Two studies were performed in beagle dogs to determine the effect of 0.2% hexetidine upon plaque and gingivitis. In both instances, hexetidine exerted no significant effect while 0.2% chlorhexidine resulted in reductions in both plaque and gingivitis of about 45 and 50%, respectively.