Reithe P, Stoll B
Dtsch Zahnarztl Z. 1977 Sep;32(9):753-4.
In a clinical study, the influence of chlorhexidine digluconate (0.1%) on the incidence of dental plaque and gingivitis was examined in subjects with insufficient personal oral hygiene. Statistical evaluation showed that compared to a placebo, chlorhexidine digluconate had a significant plaque inhibiting effect. The gingivo-therapeutic effect of this substance was statistically significant.