Uchiyama N, Stridbeck H, Stenram U
Department of Diagnostic Radiology, University Hospital Lund, Sweden.
Acta Radiol. 1989 Jul-Aug;30(4):427-31.
Chemical ablation of the gallbladder with absolute ethanol and polidocanol 3% was attempted in 23 and 10 pigs, respectively, after open transhepatic cholecystostomy. Absolute ethanol caused complete necrosis of the gallbladder epithelium in 10 pigs and partial necrosis with focally present gallbladder epithelium in 9. An intact epithelium was observed in 4 pigs but it was not possible to determine whether this epithelium was the original one, not affected by the ethanol, or regenerated after previous damage. Gallbladders with hemorrhage and hydrops were frequently encountered. Gallbladders treated with polidocanol all had an intact epithelium.
在进行开放式经肝胆囊造口术后，分别对23头猪和10头猪尝试用无水乙醇和3%聚多卡醇进行胆囊化学消融。无水乙醇导致10头猪的胆囊上皮完全坏死，9头猪的胆囊上皮部分坏死且局部仍有胆囊上皮存在。4头猪观察到上皮完整，但无法确定该上皮是未受乙醇影响的原始上皮，还是先前受损后再生的上皮。经常遇到伴有出血和积液的胆囊。用聚多卡醇治疗的胆囊上皮均完整。
