Blasi Francesco, Akova Murat, Bonanni Paolo, Dartois Nathalie, Sauty Evelyne, Webber Chris, Torres Antoni
Department of Pathophysiology and Transplantation, Università degli Studi di Milano, IRCCS Fondazione Cà Granda Ospedale Maggiore Policlinico, Milan, Italy.
Infectious Diseases Department, Hacettepe University School of Medicine, Ankara, Turkey.
Eur J Intern Med. 2017 Jan;37:13-18. doi: 10.1016/j.ejim.2016.09.024. Epub 2016 Oct 15.
Pneumococcal pneumonia remains a clear unmet medical need for adults worldwide. Despite advances in vaccine technology, vaccination coverage remains low, putting many people at risk of significant morbidity and mortality. The herd effect seen with paediatric vaccination is not enough to protect all older and vulnerable people in the community, and more needs to be done to increase the uptake of pneumococcal vaccination in adults. Several key groups are at increased risk of contracting pneumococcal pneumonia, and eligible patients are being missed in clinical practice. At present, community-acquired pneumonia costs over €10 billion annually in Europe alone. Pneumococcal conjugate vaccination could translate into preventing 200,000 cases of community-acquired pneumonia every year in Europe alone. This group calls on governments and decision makers to implement consistent age-based vaccination strategies, and for healthcare professionals in daily clinical practice to identify eligible patients who would benefit from vaccination strategies.
肺炎球菌肺炎仍是全球成年人中一项尚未得到满足的明显医疗需求。尽管疫苗技术有所进步，但疫苗接种覆盖率仍然很低，使许多人面临严重发病和死亡的风险。小儿疫苗接种所产生的群体效应不足以保护社区内所有老年人和弱势群体，需要采取更多措施来提高成人肺炎球菌疫苗的接种率。几个关键群体感染肺炎球菌肺炎的风险增加，而符合条件的患者在临床实践中被漏诊。目前，仅在欧洲，社区获得性肺炎每年的花费就超过100亿欧元。仅在欧洲，肺炎球菌结合疫苗接种每年就可以预防20万例社区获得性肺炎。该组织呼吁各国政府和决策者实施一致的基于年龄的疫苗接种策略，并要求医疗保健专业人员在日常临床实践中识别出能从疫苗接种策略中受益的符合条件的患者。
