van Vliet C, Swaen G M, Meijers J M, Slangen J, de Boorder T, Sturmans F
Department of Occupational and Environmental Health, University of Limburg, Maastricht, The Netherlands.
Br J Ind Med. 1989 Aug;46(8):586-90. doi: 10.1136/oem.46.8.586.
A population of 379 Dutch workers exposed to organic solvents was compared with a non-exposed population of 443 workers with regard to the prevalence of prenarcotic and neuraesthenic symptoms. Participants completed a questionnaire to collect information about their occupational history, exposure to organic solvents, and the occurrence of symptoms. The results of the study indicated that workers exposed to solvents have a higher reporting rate of prenarcotic symptoms than workers not exposed to solvents. The prevalence of chronic neurotoxic effects, however, in the form of neuraesthenic symptoms was only weakly associated with reported exposure to organic solvents. The influence of work stress in the development of these symptoms is perhaps more important than the role of exposure to organic solvents. It is concluded that the organic solvent syndrome type I, as defined by an international workshop, is not an important health hazard among Dutch painters.
将379名接触有机溶剂的荷兰工人与443名未接触有机溶剂的工人在麻醉前症状和神经衰弱症状的患病率方面进行了比较。参与者填写了一份问卷，以收集有关他们职业史、有机溶剂接触情况以及症状发生情况的信息。研究结果表明，接触溶剂的工人麻醉前症状的报告率高于未接触溶剂的工人。然而，以神经衰弱症状形式出现的慢性神经毒性效应的患病率与报告的有机溶剂接触情况仅存在微弱关联。工作压力对这些症状发展的影响可能比有机溶剂接触的作用更为重要。得出的结论是，国际研讨会定义的I型有机溶剂综合征在荷兰油漆工中并非重要的健康危害。
