Huang Yan-Ping, Zheng Tao, Zhang Dan-Huan, Chen Ling-Yun, Mao Pei-Jv
a Department of Nephrology , Tongren Hospital Shanghai Jiao Tong University School of Medicine , Shanghai , China.
b Institute of Image Communication and Networking , Shanghai Jiao Tong University , Shanghai , China.
Ren Fail. 2016 Nov;38(10):1672-1676. doi: 10.1080/0886022X.2016.1229987. Epub 2016 Oct 19.
To investigate the prevalence and risk factors for chronic kidney disease (CKD) among community elderly population in Shanghai, China, in order to provide early diagnosis and treatment of CKD, and improve the quality of life for elderly people.
In all, 24,886 residents (≥65 years old) were selected from community population in Changning District of Shanghai, China in 2014. They were interviewed and tested for reduced renal function estimated GFR by CKD-EPI equation. The associations among demographic characteristics, healthy characteristics (e.g., cardiovascular disease and hypertension), and indicators of kidney damage were examined.
Approximately, 16.4% of the participants were CKD. The average of them was 74.9 ± 7.0 years old. Females had a significantly higher prevalence of CKD than males (17.6% vs. 14.9%). CKD patients were present in higher prevalence of female, hyperuricemia (29.6% vs. 18.7%), hypertension (45.1% vs. 40.3%), and cardiovascular disease (23.2% vs. 18.7%) than that of non-CKD population. CKD patients were present in lower prevalence of drinking than that of non-CKD population. The prevalence of CKD in female is 2.002 times than that of male. The prevalence of CKD increased 1.048 times with the age of each increase in 1 year old. The risk factors for CKD are age, female, hyperuricemia, cardiovascular disease, hypertension, hypercholesterolemia, and smoking.
The prevalence of CKD is high in the elderly population than that of adult CKD in Shanghai. The most risk factors for elderly CKD patients are similar to the adult population. But hypercholesterolemia as a risk fact of elderly CKD is different from adult CKD.
调查中国上海社区老年人群慢性肾脏病(CKD)的患病率及危险因素,以便为CKD的早期诊断和治疗提供依据,提高老年人生活质量。
2014年从中国上海长宁区社区人群中选取24886名居民(≥65岁)。对他们进行访谈,并采用CKD-EPI方程检测估算的肾小球滤过率降低情况,以评估肾功能。研究人口统计学特征、健康特征(如心血管疾病和高血压)与肾脏损伤指标之间的关联。
约16.4%的参与者患有CKD。他们的平均年龄为74.9±7.0岁。女性CKD患病率显著高于男性(17.6%对14.9%)。与非CKD人群相比,CKD患者中女性、高尿酸血症(29.6%对18.7%)、高血压(45.1%对40.3%)和心血管疾病(23.2%对18.7%)的患病率更高。CKD患者饮酒的患病率低于非CKD人群。女性CKD患病率是男性的2.002倍。CKD患病率随年龄每增加1岁增加1.048倍。CKD的危险因素包括年龄、女性、高尿酸血症、心血管疾病、高血压、高胆固醇血症和吸烟。
上海老年人群中CKD患病率高于成年CKD人群。老年CKD患者的主要危险因素与成年人群相似。但高胆固醇血症作为老年CKD的危险因素与成年CKD不同。