Teive Hélio A G, Bertucci Délcio C, Munhoz Renato P
Universidade Federal do Paraná, Hospital de Clínicas, Serviço de Neurologia, Unidade de Distúrbios do Movimento, Curitiba PR, Brasil.
Universidade Estadual de Ponta Grossa, Departamento de Medicina Interna, Serviço de Neurologia, Ponta Grossa PR, Brasil.
Arq Neuropsiquiatr. 2016 Oct;74(10):781-784. doi: 10.1590/0004-282X20160126.
Patients with Parkinson's disease (PD) may present with unusual motor and non-motor symptoms and signs in the early stage of the disease.
Cases were collected over a five-year period at two tertiary movement disorders clinics. All had a diagnosis of PD with unusual presentations defined retrospectively as the presence of complaints not objectively related to any of the classic cardinal signs of parkinsonism or the typical early non-motor features of PD.
A total of 15 early PD patients fulfilled the proposed criteria, presenting with symptoms such as atypical tremors, shoulder pain, signs related to the rigid akinetic syndrome, as well as cases of asthenia, rhinorrhea, parosmia, dysgeusia, nocturnal sialorrhea, and color discrimination disorders.
Unusual motor and non-motor symptoms and signs in the early stage of PD can be difficult to interpret. Specialists should be aware of these conditions as clues to a potential diagnosis.
帕金森病（PD）患者在疾病早期可能出现不寻常的运动和非运动症状及体征。
在两家三级运动障碍诊所收集了为期五年的病例。所有病例均诊断为PD，其不寻常表现被回顾性定义为存在与帕金森病任何经典主要体征或PD典型早期非运动特征无客观关联的主诉。
共有15例早期PD患者符合拟定标准，表现出非典型震颤、肩部疼痛、与强直少动综合征相关的体征，以及乏力、鼻溢、嗅觉异常、味觉障碍、夜间流涎和色觉障碍等症状。
PD早期不寻常的运动和非运动症状及体征可能难以解释。专科医生应将这些情况视为潜在诊断的线索。
