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棘球蚴病肺动脉梗阻的腔内超声检查

Endosonography of a Pulmonary Artery Obstruction in Echinococcosis.

作者信息

Schuuring Mark J, Bonta Peter I, van Vugt Michele, Smithuis Frank, van Delden Otto M, Annema Jouke T, Stijnis Kees

机构信息

Department of Internal Medicine, Academic Medical Center, Amsterdam, The Netherlands.

出版信息

Respiration. 2016;92(6):425-427. doi: 10.1159/000451031. Epub 2016 Oct 20.

Abstract

A 44-year-old woman with a history of pulmonary embolism and abdominal echinococcosis complained of sudden thoracic pain and shortness of breath. A D-dimer of 77.5 mg/l (reference ≤0.5 mg/l) was found. Chest CT scan revealed obstruction of the right lower and middle lobe pulmonary artery (PA). Anticoagulation therapy was initiated for the presumed diagnosis of recurrent pulmonary embolism. However, due to persistent symptoms of dyspnea, follow-up CT angiography of the chest was performed 3 months later. A persistent PA obstruction was found and the presumed diagnosis of embolism was questioned. Subsequently, endobronchial ultrasound (EBUS) imaging was performed to support an alternative diagnosis. EBUS imaging showed an inhomogeneous, sharply demarcated, intravascular lesion with round hypoechoic areas compatible with cysts. The diagnosis of embolism was rejected and treatment with albendazole was initiated for pulmonary echinococcosis. Echinococcosis is a parasitic disease and cystic spread in the PA is exceptional. The patient has remained stable for more than 4 years. In case of disease progression, including progressive PA obstruction or life-threatening hemoptysis, surgical resection will be considered.

摘要

一名有肺栓塞和腹部包虫病病史的44岁女性,主诉突发胸痛和气短。发现D-二聚体为77.5mg/l(参考值≤0.5mg/l)。胸部CT扫描显示右下和中叶肺动脉(PA)阻塞。因推测为复发性肺栓塞而开始抗凝治疗。然而,由于持续存在呼吸困难症状,3个月后进行了胸部CT血管造影随访。发现PA持续阻塞,对栓塞的推测诊断受到质疑。随后,进行了支气管内超声(EBUS)成像以支持另一种诊断。EBUS成像显示一个不均匀、边界清晰的血管内病变,有与囊肿相符的圆形低回声区。排除了栓塞诊断,开始用阿苯达唑治疗肺包虫病。包虫病是一种寄生虫病,囊肿在PA内播散很罕见。该患者已稳定超过4年。如果疾病进展,包括进行性PA阻塞或危及生命的咯血,将考虑手术切除。

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