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1918年的流感是否导致了美国20世纪心血管疾病死亡率的激增?

Did the 1918 influenza cause the twentieth century cardiovascular mortality epidemic in the United States?

作者信息

Tate Steven, Namkung Jamie J, Noymer Andrew

机构信息

Pritzker School of Medicine, University of Chicago , Chicago , IL , United States.

Program in Public Health, University of California , Irvine , CA , United States.

出版信息

PeerJ. 2016 Oct 4;4:e2531. doi: 10.7717/peerj.2531. eCollection 2016.

DOI:10.7717/peerj.2531
PMID:27761328
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5068420/
Abstract

During most of the twentieth century, cardiovascular mortality increased in the United States while other causes of death declined. By 1958, the age-standardized death rate (ASDR) for cardiovascular causes for females was 1.84 times that for all other causes, (and, for males, 1.79×). Although contemporary observers believed that cardiovascular mortality would remain high, the late 1950s and early 1960s turned out to be the peak of a roughly 70-year epidemic. By 1988 for females (1986 for males), a spectacular decline had occurred, wherein the ASDR for cardiovascular causes was less than that for other causes combined. We discuss this phenomenon from a demographic point of view. We also test a hypothesis from the literature, that the 1918 influenza pandemic caused the cardiovascular mortality epidemic; we fail to find support.

摘要

在20世纪的大部分时间里,美国心血管疾病死亡率上升,而其他死因的死亡率则下降。到1958年,女性心血管疾病的年龄标准化死亡率(ASDR)是所有其他死因的1.84倍(男性为1.79倍)。尽管当时的观察家认为心血管疾病死亡率将居高不下,但20世纪50年代末和60年代初却是一场持续约70年的流行病的高峰期。到1988年(女性)和1986年(男性),心血管疾病死亡率出现了显著下降,心血管疾病的年龄标准化死亡率低于其他死因的总和。我们从人口统计学角度讨论这一现象。我们还检验了文献中的一个假设,即1918年的流感大流行导致了心血管疾病死亡率的流行,但未找到支持证据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc59/5068420/af9e172747b6/peerj-04-2531-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc59/5068420/2195a46943b4/peerj-04-2531-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc59/5068420/85c3f54f04cc/peerj-04-2531-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc59/5068420/8f9ef3a6e982/peerj-04-2531-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc59/5068420/a066dd02b3e2/peerj-04-2531-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc59/5068420/af9e172747b6/peerj-04-2531-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc59/5068420/2195a46943b4/peerj-04-2531-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc59/5068420/85c3f54f04cc/peerj-04-2531-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc59/5068420/8f9ef3a6e982/peerj-04-2531-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc59/5068420/a066dd02b3e2/peerj-04-2531-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc59/5068420/af9e172747b6/peerj-04-2531-g005.jpg

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