Liu Wenzhong, Zhang Hao F
Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208,USA.
Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208,USA; Department of Ophthalmology, Northwestern University, Chicago, IL 60611, USA.
Photoacoustics. 2016 May 18;4(3):112-123. doi: 10.1016/j.pacs.2016.05.001. eCollection 2016 Sep.
The eye relies on the synergistic cooperation of many different ocular components, including the cornea, crystalline lens, photoreceptors, and retinal neurons, to precisely sense visual information. Complications with a single ocular component can degrade vision and sometimes cause blindness. Immediate treatment and long-term monitoring are paramount to alleviate symptoms, restore vision, and cure ocular diseases. However, successful treatment requires understanding ocular pathological mechanisms, precisely detecting and monitoring the diseases. The investigation and diagnosis of ocular diseases require advanced medical tools. In this mini review, we discuss non-invasive photoacoustic (PA) imaging as a potential research tool and medical screening device. In the research setting, PA imaging can provide valuable information on the disease progression. In the clinical setting, PA imaging can potentially aid in disease detection and treatment monitoring.
眼睛依靠许多不同眼部组件的协同合作，包括角膜、晶状体、光感受器和视网膜神经元，来精确感知视觉信息。单个眼部组件出现问题会导致视力下降，有时甚至会导致失明。立即治疗和长期监测对于缓解症状、恢复视力和治愈眼部疾病至关重要。然而，成功的治疗需要了解眼部病理机制，精确检测和监测疾病。眼部疾病的研究和诊断需要先进的医疗工具。在本综述中，我们将讨论非侵入性光声（PA）成像作为一种潜在的研究工具和医学筛查设备。在研究环境中，PA成像可以提供有关疾病进展的有价值信息。在临床环境中，PA成像可能有助于疾病检测和治疗监测。
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