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高性能光声显微镜系统的全面综述。

A comprehensive review of high-performance photoacoustic microscopy systems.

作者信息

Park Eunwoo, Kim Donggyu, Ha Mingyu, Kim Donghyun, Kim Chulhong

机构信息

Department of Convergence IT Engineering, Electrical Engineering, Mechanical Engineering, Medical Science and Engineering, Graduate School of Artificial Intelligence, and Medical Device Innovation Center, Pohang University of Science and Technology (POSTECH), Pohang, Republic of Korea.

Opticho Inc., Pohang, Republic of Korea.

出版信息

Photoacoustics. 2025 Jun 4;44:100739. doi: 10.1016/j.pacs.2025.100739. eCollection 2025 Aug.

DOI:10.1016/j.pacs.2025.100739
PMID:40528993
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12173134/
Abstract

Photoacoustic microscopy (PAM), an imaging modality with emerging importance in diverse biomedical applications, provides excellent structural and functional information at the micro-scale. Technological innovations have significantly enhanced PAM's performance, including sensitivity and contrast, making it a powerful tool. This review explores high-performance PAM, focusing on its signal-to-noise ratio, imaging speed, resolution, depth, functionality, and practicality, and commenting on the role of artificial intelligence in enhancing each feature. After providing comprehensive insights, the review concludes with future directions for developing high-performance PAM for advanced biomedical imaging and clinical applications.

摘要

光声显微镜（PAM）是一种在各种生物医学应用中日益重要的成像方式，可在微观尺度上提供出色的结构和功能信息。技术创新显著提高了PAM的性能，包括灵敏度和对比度，使其成为一种强大的工具。本综述探讨了高性能PAM，重点关注其信噪比、成像速度、分辨率、深度、功能和实用性，并评论了人工智能在增强每个特性方面的作用。在提供全面的见解之后，本综述最后给出了开发用于先进生物医学成像和临床应用的高性能PAM的未来方向。

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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ced/12173134/3a8729f72e1c/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ced/12173134/66cedb5a3ead/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ced/12173134/63d36a247b5f/gr8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ced/12173134/146d6483b7af/gr9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ced/12173134/015af89d01dc/gr10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ced/12173134/e6a574db5590/gr11.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ced/12173134/d030dc4feeeb/gr12.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ced/12173134/a3d48c7dbedd/gr13.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ced/12173134/05a4d041ee84/gr14.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ced/12173134/1ab4546718e0/gr15.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ced/12173134/e04333f15f2f/gr16.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ced/12173134/86f07c790ba3/gr17.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ced/12173134/89c40b2f722f/gr18.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ced/12173134/2f615ffb9f13/gr19.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ced/12173134/148b49375a84/gr20.jpg

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