Pincus Theodore
Department of Internal Medicine, Division of Rheumatology, Rush University Medical Center, Chicago, IL, USA.
Clin Exp Rheumatol. 2016 Sep-Oct;34(5 Suppl 101):S49-S53. Epub 2016 Oct 18.
RAPID3 (routine assessment of patient index data) is an index found within a multi-dimensional health assessment questionnaire (MDHAQ) for routine clinical care, composed only of 3 self-report scores for physical function, pain, and patient global estimate, each scored 0-10, for a total of 0-30. RAPID3 is correlated significantly with DAS28 (Disease Activity Score) and CDAI (Clinical Disease Activity Index), and distinguishes active from control treatments as efficiently as these indices in clinical trials involving adalimumab, abatacept, certolizumab, infliximab, and rituximab. Many versions of an electronic RAPID3 (eRAPID3) have been developed, which are incompatible with one another, as seen for electronic medical records (EMR). Therefore, opportunities are lost to pool data from many sites for advancement of patient care and outcomes. Interfaces for linkage to EMRs and pooling of data are available as Health Level Seven (HL7) standards, FHIR (Fast Health Interoperability Resources), and innovative open platforms like SMART (Substitutable Medical Apps, Reusable Technology), but many eRAPID3 versions do not have this capacity. RAPID3 scores may be elevated in many patients due to damage or distress, rather than, or in addition to, inflammation, a problem that also affects DAS28, CDAI, and all RA indices which include a patient global estimate, even if they include a formal joint count. A full MDHAQ, of which RAPID3 is a component, provides clues to the presence of damage, and/or distress and adds much further information, with no more work for the health professional and little more time for the patient. A RheuMetric physician checklist of global scores for inflammation, damage, and distress is also useful to recognise damage and/or distress, but not available with most available eRAPID3 versions. Many eRAPID3 versions also are limited by the absence of flowsheets to monitor scores over time, the absence of strategies to convey data to health professionals to improve care, and the absence of advanced features for patients and doctors which are available in some versions of an eRAPID3. It is recommended that eRAPID3 should include a full MDHAQ, RheuMetric checklist, a longitudinal flowsheet of scores, and a defined strategy for management of the data to be available to the physician for improved patient care, to enhance value and quantitative interpretation of RAPID3 scores.
RAPID3(患者指标数据常规评估)是一种存在于用于常规临床护理的多维健康评估问卷(MDHAQ)中的指数,仅由身体功能、疼痛和患者整体评估这3个自我报告评分组成,每个评分范围为0至10分,总分0至30分。RAPID3与DAS28(疾病活动评分)和CDAI(临床疾病活动指数)显著相关,并且在涉及阿达木单抗、阿巴西普、赛妥珠单抗、英夫利昔单抗和利妥昔单抗的临床试验中,与这些指数一样有效地区分了活性治疗与对照治疗。已经开发了许多版本的电子RAPID3(eRAPID3),但它们彼此不兼容,就像电子病历(EMR)一样。因此,失去了汇集多个站点数据以推进患者护理和改善治疗结果的机会。作为健康级别7(HL7)标准、FHIR(快速健康互操作性资源)以及像SMART(可替代医疗应用程序、可重复使用技术)这样的创新开放平台,存在与EMR链接和数据汇集的接口,但许多eRAPID3版本没有这种能力。由于损伤或痛苦,许多患者的RAPID3评分可能会升高,而不是炎症,或者除炎症之外,这也是一个影响DAS28、CDAI以及所有包含患者整体评估的类风湿关节炎指数的问题,即使它们包括正式的关节计数。RAPID3作为其组成部分的完整MDHAQ提供了损伤和/或痛苦存在的线索,并增加了更多信息,对健康专业人员来说工作量没有增加,对患者来说时间也几乎没有增加。一份关于炎症、损伤和痛苦全球评分的RheuMetric医生检查表对于识别损伤和/或痛苦也很有用,但大多数可用的eRAPID3版本都没有。许多eRAPID3版本还受到以下限制:缺乏随时间监测评分的流程图,缺乏将数据传达给健康专业人员以改善护理的策略,以及缺乏某些eRAPID3版本中为患者和医生提供的高级功能。建议eRAPID3应包括完整的MDHAQ、RheuMetric检查表、评分的纵向流程图以及为医生提供的用于改善患者护理的明确数据管理策略,以提高RAPID3评分的价值和定量解释。