[凝集素受体在卵巢囊腺瘤和囊腺癌中的分布]
[Distribution of lectin-receptors in ovarian cystadenoma and cystadenocarcinoma].
作者信息
Hu N P
出版信息
Zhonghua Bing Li Xue Za Zhi. 1989 Mar;18(1):40-2.
55 cases of ovarian cystadenoma and cystadenocarcinoma were investigated with a panel of twelve various lectins and ABC technique. Results showed that RCA and WGA reacted with all the tumors, indicating that these two lectins are possibly functional differential markers of both ovarian mucinous and serous tumors. LCA, DBA and SJA might be of considerable help in differential diagnosis of serous cystadenoma and cystadenocarcinoma. PSA probably was a marker indicating malignant change of mucinous cystadenmas. Since there were different reactivities in mucinous and serous cystadenoma, SJA, DBA and SBA might be considered as the functional markers in differentiating these two different types of ovarian cystadenoma.
采用一组12种不同的凝集素和ABC技术对55例卵巢囊腺瘤和囊腺癌进行了研究。结果显示，蓖麻凝集素（RCA）和麦胚凝集素（WGA）与所有肿瘤均发生反应，表明这两种凝集素可能是卵巢黏液性和浆液性肿瘤的功能性鉴别标志物。刀豆球蛋白A（LCA）、大豆凝集素（DBA）和荆豆凝集素（SJA）可能对浆液性囊腺瘤和囊腺癌的鉴别诊断有很大帮助。前列腺特异性抗原（PSA）可能是黏液性囊腺瘤恶变的标志物。由于黏液性和浆液性囊腺瘤存在不同的反应性，SJA、DBA和大豆凝集素（SBA）可被视为区分这两种不同类型卵巢囊腺瘤的功能性标志物。
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