Okamoto M, Fukasawa H, Hirata F, Hoshi S
Gan To Kagaku Ryoho. 1984 Feb;11(2):240-6.
In this paper, we presented an interesting case with a cystic ovarian tumor, which consisted of the mucinous cystadenoma and the mucinous cystadenocarcinoma separated by a partition. The determination of ferritin concentrations in the both displayed ferritin levels of 87.5 ng/ml in the former and 14,812.0 ng/ml in latter respectively. This fact suggested the production of ferritin by the malignant tumor cells. To clarify this possibility, measurement of ferritin levels in the content of cystic ovarian tumors in fifteen cases and in the ascites of various origin in sixty-five cases was done. This study also supported a possibility that malignant tumor cells produce and/or secrete much more ferritin into the body fluid than benign tumor cells.
在本文中,我们呈现了一例有趣的卵巢囊性肿瘤病例,该肿瘤由黏液性囊腺瘤和黏液性囊腺癌组成,二者被一隔膜分隔。对两者中 ferritin 浓度的测定显示,前者的 ferritin 水平为 87.5 ng/ml,后者为 14,812.0 ng/ml。这一事实提示恶性肿瘤细胞产生 ferritin。为阐明这种可能性,我们对 15 例卵巢囊性肿瘤内容物及 65 例不同来源腹水的 ferritin 水平进行了测定。该研究也支持了一种可能性,即恶性肿瘤细胞比良性肿瘤细胞向体液中产生和/或分泌更多的 ferritin。