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[女性II型糖尿病、冠心病、原发性高血压患者性激素变化及其与肾虚、心血管并发症以及中医或气功治疗疗效的关系]

[Changes of the sex hormones in female type II diabetics, coronary heart disease, essential hypertension and its relations with kidney deficiency, cardiovascular complications and efficacy of traditional Chinese medicine or qigong treatment].

作者信息

Kuang A K, Chen J L, Lu Y R

出版信息

Zhong Xi Yi Jie He Za Zhi. 1989 Jun;9(6):331-4, 323.

PMID:2776274
Abstract

In this study 31 normal child-bearing women, 62 postmenopausal women, 93 cases of female type II diabetes (18 child-bearing and 75 postmenopausal cases), 53 cases of coronary heart disease (11 child-bearing and 42 postmenopausal cases) and 38 cases of essential hypertension (8 child-bearing and 30 postmenopausal cases) were investigated. The average score of Kidney deficiency was 22.9-8. 5 before treatment with the combination of TCM and WM. With the treatment of TCM in diabetes and coronary heart disease and of Qigong in essential hypertension, the score decreased to 11.5-4. 4 (P less than 0.001). Serum/saliva estradiol (E2), the ratio of E2 to testosterone (T, E2/T) and progesterone (P) decreased before treatment of TCM or Qigong. After treatment E2 and P value increased; the ovarian endocrine function was improved; the special symptoms of the diseases relieved, fasting blood glucose levels in diabetics, the frequency and severity of angina pectoris in coronary heart disease and the blood pressure in essential hypertension significantly decreased respectively (P less than 0.01). The study suggested that there are certain relations between ovarian endocrine disfunction and Kidney deficiency. The more severe the "Kidney deficiency" was, the more significant the changes of sex hormone were.

摘要

本研究对31名正常育龄妇女、62名绝经后妇女、93例Ⅱ型女性糖尿病患者(其中18例育龄期患者,75例绝经后患者)、53例冠心病患者(其中11例育龄期患者,42例绝经后患者)以及38例原发性高血压患者(其中8例育龄期患者,30例绝经后患者)进行了调查。中西医结合治疗前肾虚平均评分为22.9 - 8.5。经中医治疗糖尿病和冠心病以及气功治疗原发性高血压后,评分降至11.5 - 4.4(P < 0.001)。中医或气功治疗前血清/唾液雌二醇(E2)、E2与睾酮(T,E2/T)的比值以及孕酮(P)均降低。治疗后E2和P值升高;卵巢内分泌功能得到改善;疾病的特殊症状缓解,糖尿病患者空腹血糖水平、冠心病患者心绞痛发作频率和严重程度以及原发性高血压患者血压分别显著下降(P < 0.01)。研究表明,卵巢内分泌功能障碍与肾虚之间存在一定关系。“肾虚”越严重,性激素变化越显著。

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