通过原位杂交将编码新型垂体多肽7B2的人类基因定位到15号染色体q13----q14区域。
Regional mapping of the human gene encoding the novel pituitary polypeptide 7B2 to chromosome 15q13----q14 by in situ hybridization.
作者信息
Roebroek A J, Dehaen M R, van Bokhoven A, Martens G J, Marÿnen P, van den Berghe H, Van de Ven W J
机构信息
Department of Biochemistry, University of Nijmegen, The Netherlands.
出版信息
Cytogenet Cell Genet. 1989;50(2-3):158-60. doi: 10.1159/000132749.
Genetic sequences encoding the novel pituitary polypeptide 7B2 were isolated from a human pituitary cDNA library. Hybridization analysis of a panel of human x mouse cell hybrids with a 7B2 cDNA probe indicated that the locus for the human 7B2 gene is probably located on chromosome 15. In situ hybridization analysis of metaphase chromosomes allowed the regional localization of the 7B2 gene to chromosome 15 at q13----q14.
从人垂体cDNA文库中分离出编码新型垂体多肽7B2的基因序列。用7B2 cDNA探针分析一组人-鼠细胞杂种，结果表明人7B2基因的位点可能位于15号染色体上。对中期染色体进行原位杂交分析，将7B2基因定位到15号染色体的q13----q14区域。
Zotero 插件