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[大网膜移植治疗脊髓损伤的实验研究]

[Experimental study on the treatment of spinal cord injury with transplantation of the greater omentum].

作者信息

Zheng W J

出版信息

Zhonghua Wai Ke Za Zhi. 1989 Feb;27(2):93-5, 125.

PMID:2776547
Abstract

The effects of pedicled omentum transplantation without vascular anastomosis in treating traumatic spinal cord injury in animals were observed. The shaped omentum was spread on the surface area of the injured part of the cord with its edges stitched to the cut-open edges of dura matter. Six hours later, the transplanted omentum and the covered cord surface stick together, becoming tighter and tighter with the time on until the omentum, arachnoid and pia matter stick fast. At the same time, newly developing capillaries sprouted out on the cord surface, growing inwards into the white matter upto 0.2mm at about 3 to 4 weeks; there mixing with neurofibers. During this period of time, (1 to 4 wks. after transplantation), the pathology in the treated group and the control group were obviously different: the focal hemorrhage, the necrosis of neurocytes and the degeneration of neurofibers were much less in degree and extent in the former group than that in the latter; the survivors of neurocytes and neurofibers were also great more in the treated group.

摘要

观察了带蒂大网膜无血管吻合移植对动物创伤性脊髓损伤的治疗作用。将塑形后的大网膜铺展于脊髓损伤部位表面,其边缘与硬脊膜切开边缘缝合。6小时后,移植的大网膜与覆盖的脊髓表面粘连在一起,随着时间推移越来越紧密,直至大网膜、蛛网膜和软膜牢固粘连。同时,脊髓表面有新生毛细血管芽长出,约3至4周时向白质内生长达0.2mm;在白质内与神经纤维混合。在此期间(移植后1至4周),治疗组与对照组的病理改变明显不同:前者局灶性出血、神经细胞坏死及神经纤维变性的程度和范围均明显轻于后者;治疗组神经细胞和神经纤维的存活数量也明显多于后者。

相似文献

1
[Experimental study on the treatment of spinal cord injury with transplantation of the greater omentum].[大网膜移植治疗脊髓损伤的实验研究]
Zhonghua Wai Ke Za Zhi. 1989 Feb;27(2):93-5, 125.
2
[Experimental study on effects of omental transposition in cats with spinal cord injury].[大网膜移位对猫脊髓损伤影响的实验研究]
No To Shinkei. 1995 Sep;47(9):863-73.
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[Observations on the effect of omental transplantation to the traumatized spinal cord].[关于网膜移植对创伤性脊髓影响的观察]
Zhonghua Wai Ke Za Zhi. 1989 Jan;27(1):48-51, 62-3.
4
Early application of pedicled omentum to the acutely traumatised spinal cord.带蒂大网膜早期应用于急性创伤性脊髓损伤
Paraplegia. 1985 Apr;23(2):100-12. doi: 10.1038/sc.1985.18.
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[Omentum transplantation to the cervical cord with microangioanastomosis].[带微血管吻合术的大网膜移植至颈髓]
No Shinkei Geka. 1991 Apr;19(4):309-18.
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[The results of omentomyelopexy in the late period of traumatic spinal cord disease].[外伤性脊髓病晚期大网膜脊髓固定术的结果]
Zh Vopr Neirokhir Im N N Burdenko. 1998 Apr-Jun(2):17-9.
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[Effects of different methods of fetal spinal cord tissue transplanted on reversing the axotomy-induced neurons atrophy rats injured spinal cord].
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2001 Mar;15(2):65-8.
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Early angiogenic capabilities of the transposed omental flap after omentomyelopexy.网膜脊髓固定术后转位大网膜瓣的早期血管生成能力。
Acta Chir Iugosl. 2001;48(2):41-3.
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[Therapeutic effects of pedicled great omentum transplantation in treating traumatic paraplegia].带蒂大网膜移植治疗外伤性截瘫的疗效观察
Zhonghua Wai Ke Za Zhi. 1987 Jun;25(6):351-2, 381-2.
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Acute transplantation of olfactory ensheathing cells or Schwann cells promotes recovery after spinal cord injury in the rat.急性移植嗅鞘细胞或雪旺细胞可促进大鼠脊髓损伤后的恢复。
J Neurosci Res. 2004 Mar 1;75(5):632-41. doi: 10.1002/jnr.20029.

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