Feifel David, Pappas Katherine
Department of Psychiatry, University of California, San Diego;
Department of Psychiatry, University of California, San Diego.
J Vis Exp. 2016 Oct 4(116):53858. doi: 10.3791/53858.
Repetitive transcranial magnetic stimulation (rTMS) is an emerging non-pharmacological approach to treating many brain-based disorders. rTMS uses electromagnetic coils to stimulate areas of the brain non-invasively. Deep transcranial magnetic stimulation (dTMS) with the Brainsway H1-coil system specifically is a type of rTMS indicated for treating patients with major depressive disorder (MDD) who are resistant to medication. The unique H1-coil design of this device is able to stimulate neuronal pathways that lie deeper in the targeted brain areas than those reached by conventional rTMS coils. dTMS is considered to be low-risk and well tolerated, making it a viable treatment option for people who have not responded to medication or psychotherapy trials for their depression. Randomized, sham-control studies have demonstrated that dTMS produces significantly greater improvement in depressive symptoms than sham dTMS treatment in patients with major depression that has not responded to antidepressant medication. In this paper, we will review the methodology for treating major depression with dTMS using an H1-coil.
重复经颅磁刺激（rTMS）是一种新兴的非药物治疗方法，用于治疗多种基于大脑的疾病。rTMS使用电磁线圈对大脑区域进行非侵入性刺激。特别是采用Brainsway H1线圈系统的深部经颅磁刺激（dTMS）是rTMS的一种类型，适用于治疗对药物治疗有抵抗性的重度抑郁症（MDD）患者。该设备独特的H1线圈设计能够刺激比传统rTMS线圈所触及的目标脑区更深层的神经通路。dTMS被认为风险较低且耐受性良好，这使其成为那些对抑郁症的药物治疗或心理治疗试验无反应的人的一种可行治疗选择。随机、假对照研究表明，在对抗抑郁药物无反应的重度抑郁症患者中，dTMS比假dTMS治疗能显著改善抑郁症状。在本文中，我们将回顾使用H1线圈进行dTMS治疗重度抑郁症的方法。
