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翻修固定、同种异体移植及辅助细胞疗法治疗儿童股骨颈骨不连

Refixation, allograft and adjuvant cell therapy to treat nonunion of the femoral neck in a child.

作者信息

Magnani Marina, Trisolino Giovanni, Stilli Stefano

机构信息

Complex Structure of Paediatric Orthopaedics and Traumatology, Rizzoli Orthopaedic Institute, Bologna - Italy.

出版信息

Hip Int. 2016 Nov 10;26(6):e45-e48. doi: 10.5301/hipint.5000453.

DOI:10.5301/hipint.5000453
PMID:27768215
Abstract

INTRODUCTION

Idiopathic posttraumatic nonunion is a rare condition in children; the treatment of this complication is still controversial in this peculiar population.

CASE REPORT

We report a case of a subcapital type II femoral neck fracture, in a 12-year-old boy, which was initially treated by internal fixation and subsequently went on to a nonunion at the femoral neck, in absence of infection or other disease.1 year after index surgery we performed surgical debridement and refixation with plate and bone allograft, added with autologous bone marrow aspiration concentrate (BMAC) and platelet-rich fibrin (PRF).After 3 months the nonunion healed and the boy was allowed full weight-bearing.

CONCLUSIONS

Combined surgery and adjuvant cell therapy can be considered an option of treatment in nonunion of the femoral neck in the paediatric population.

摘要

引言

儿童特发性创伤后骨不连是一种罕见病症;在这一特殊人群中,该并发症的治疗仍存在争议。

病例报告

我们报告一例12岁男孩的II型股骨颈头下型骨折,最初采用内固定治疗,随后在无感染或其他疾病的情况下发生股骨颈骨不连。初次手术后1年,我们进行了手术清创,并用钢板和同种异体骨移植重新固定,同时添加了自体骨髓抽吸浓缩物(BMAC)和富血小板纤维蛋白(PRF)。3个月后骨不连愈合,该男孩被允许完全负重。

结论

联合手术及辅助细胞治疗可被视为小儿股骨颈骨不连的一种治疗选择。

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Hip Int. 2016 Nov 10;26(6):e45-e48. doi: 10.5301/hipint.5000453.
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