达那唑对不明原因的原发性不孕症是否是一种有效的治疗方法？

Is danazol a useful treatment in unexplained primary infertility?

作者信息

Iffland C A, Shaw R W, Beynon J L

机构信息

Academic Department of Obstetrics and Gynaecology, Royal Free Hospital, London.

出版信息

Eur J Obstet Gynecol Reprod Biol. 1989 Aug;32(2):115-21. doi: 10.1016/0028-2243(89)90192-5.

DOI:10.1016/0028-2243(89)90192-5

PMID:2776952

Abstract

39 patients with primary unexplained infertility were treated in a double-blind placebo-controlled study of danazol. 14 patients completed a treatment course of danazol and 17 of placebo. One patient in the placebo group conceived during the 12 months follow-up period, and none in the danazol group. Danazol does not seem to be an effective treatment for unexplained primary infertility.

摘要

在一项关于达那唑的双盲安慰剂对照研究中，对39例原发性不明原因不孕症患者进行了治疗。14例患者完成了达那唑治疗疗程，17例完成了安慰剂治疗疗程。安慰剂组有1例患者在12个月的随访期内怀孕，达那唑组无患者怀孕。达那唑似乎不是治疗不明原因原发性不孕症的有效方法。