Treatment of unexplained infertility with danazol.

In order to investigate the possible stimulatory effect of danazol on fertility, a randomized clinical trial was performed on 40 women with unexplained infertility. Twenty-one women received 200 mg danazol daily for 100 days and 19 women received a placebo for the same period. No pregnancies occurred in the placebo group during a 6 month follow-up period. In the danazol group, 5 pregnancies occurred of which 1 were ectopic and 3 went to term.