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通过注塑成型制备的可生物降解镁增强聚乳酸复合材料的力学性能和降解性能

Mechanical and degradation properties of biodegradable Mg strengthened poly-lactic acid composite through plastic injection molding.

作者信息

Butt Muhammad Shoaib, Bai Jing, Wan Xiaofeng, Chu Chenglin, Xue Feng, Ding Hongyan, Zhou Guanghong

机构信息

School of Materials Science and Engineering, Southeast University, Jiangning, Nanjing, 211189, Jiangsu, China; Jiangsu Key Laboratory for Advanced Metallic Materials, Jiangning, Nanjing 211189, Jiangsu, China.

School of Materials Science and Engineering, Southeast University, Jiangning, Nanjing, 211189, Jiangsu, China; Jiangsu Key Laboratory for Advanced Metallic Materials, Jiangning, Nanjing 211189, Jiangsu, China.

出版信息

Mater Sci Eng C Mater Biol Appl. 2017 Jan 1;70(Pt 1):141-147. doi: 10.1016/j.msec.2016.08.051. Epub 2016 Aug 25.

DOI:10.1016/j.msec.2016.08.051
PMID:27770873
Abstract

Full biodegradable magnesium alloy (AZ31) strengthened poly-lactic acid (PLA) composite rods for potential application for bone fracture fixation were prepared by plastic injection process in this work. Their surface/interfacial morphologies, mechanical properties and vitro degradation were studied. In comparison with untreated Mg rod, porous MgO ceramic coating on Mg surface formed by Anodizing (AO) and micro-arc-oxidation (MAO)treatment can significantly improve the interfacial binding between outer PLA cladding and inner Mg rod due to the micro-anchoring action, leading to better mechanical properties and degradation performance of the composite rods.With prolonging immersion time in simulated body fluid (SBF) solution until 8weeks, the MgO porous coating were corroded gradually, along with the disappearance of original pores and the formation of a relatively smooth surface. This resulted in a rapidly reduction in mechanical properties for corresponding composite rods owing to the weakening of interfacial binding capacity. The present results indicated that this new PLA-clad Mg composite rods show good potential biomedical applications for implants and instruments of orthopedic inner fixation.

摘要

本研究通过注塑工艺制备了用于骨折固定的全生物可降解镁合金(AZ31)增强聚乳酸(PLA)复合棒。研究了其表面/界面形貌、力学性能和体外降解情况。与未处理的镁棒相比,通过阳极氧化(AO)和微弧氧化(MAO)处理在镁表面形成的多孔氧化镁陶瓷涂层,由于微锚固作用,可显著改善外部PLA包层与内部镁棒之间的界面结合,从而使复合棒具有更好的力学性能和降解性能。随着在模拟体液(SBF)溶液中的浸泡时间延长至8周,氧化镁多孔涂层逐渐被腐蚀,原始孔隙消失,形成相对光滑的表面。由于界面结合能力减弱,相应复合棒的力学性能迅速降低。目前的结果表明,这种新型PLA包覆镁复合棒在骨科内固定植入物和器械方面具有良好的生物医学应用潜力。

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