Kringsholm B, Theilade P, Geertinger P
University Institute of Forensic Medicine, Copenhagen, Denmark.
Forensic Sci Int. 1989 Jun;41(3):281-4. doi: 10.1016/0379-0738(89)90221-1.
In 1987 a total of 89 intravenous drug addicts were admitted to medico-legal autopsy at the University Institute of Forensic Medicine in Copenhagen. Totally 10 cases were reactive by the Elisa test and five of these, or 7% of the total material tested, could be confirmed by the immuno-blotting test. The other five cases must be considered as false positive, possibly due to antibodies against cellular antigens. Among the five real positive cases, four were known before-hand while in one case the HIV-positivity was not known. These findings - together with the possibility of false negative reactions - especially regarding persons with acute HIV-infection, requires special precautionary measures when autopsies of drug addicts are performed.
1987年,哥本哈根大学法医学研究所共对89名静脉注射吸毒者进行了法医尸检。通过酶联免疫吸附测定(ELISA)检测,共有10例呈阳性反应,其中5例,即所检测全部样本的7%,可通过免疫印迹试验得到证实。另外5例必须被视为假阳性,可能是由于针对细胞抗原的抗体所致。在这5例真正的阳性病例中,有4例事先已知感染情况,而有1例的艾滋病毒阳性情况此前并不知晓。这些发现——连同假阴性反应的可能性——尤其是对于急性艾滋病毒感染患者而言,在对吸毒者进行尸检时需要采取特殊的预防措施。