Vaidya S, Khuller G K
Indian J Biochem Biophys. 1989 Apr;26(2):98-103.
Microsporum gypseum cells grown on saturated alkanes of different chain lengths (C10, C12, C14, C16 and C18) exhibited increased levels of total phospholipids and sterols. A significant increase in the content of phosphatidylcholine was observed in alkane-grown cells. Increased saturation of phospholipid fatty acid was observed with all the alkanes studied, which was mainly due to the decreased amount of C18:1 and C18:2 with concomitant increase in the levels of palmitic acid. The affinity for glycine changed in alkane-supplemented cells as compared to glucose-grown cells. 1-Anilino-naphthalene-8-sulphonate (ANS) binding to the spheroplast membrane demonstrated increased binding sites in supplemented cells. These results are discussed in terms of the effect of altered lipid composition on the membrane structure and function of this fungus.
在不同链长（C10、C12、C14、C16和C18）的饱和烷烃上生长的石膏样小孢子菌细胞，其总磷脂和甾醇水平有所增加。在烷烃培养的细胞中观察到磷脂酰胆碱含量显著增加。在所研究的所有烷烃中均观察到磷脂脂肪酸饱和度增加，这主要是由于C18:1和C18:2含量减少，同时棕榈酸水平升高。与葡萄糖培养的细胞相比，补充烷烃的细胞对甘氨酸的亲和力发生了变化。1-苯胺基萘-8-磺酸盐（ANS）与原生质球膜的结合表明，补充细胞中的结合位点增加。本文根据脂质组成改变对该真菌膜结构和功能的影响对这些结果进行了讨论。
