Beller F K, Wagner H, Büchner T
Klin Wochenschr. 1978 Jun 15;56(12):593-9. doi: 10.1007/BF01477007.
A case is presented of a pregnant patient in the 28th week of gestation with promyelocytic leukemia and an unusual thrombohemorrhagic skin lesion. Ultrastructural examination revealed a microthrombotic purpura. Reduced coagulation factors increased during heparin treatment. The exacerbation of disseminated intravascular coagulation is explained by a hypercoagulable state in pregnancy in association with the as yet unknown etiology of "promyelocytic fibrinopathic leukemia".
本文报告一例妊娠28周的孕妇,患有早幼粒细胞白血病,并伴有一种罕见的血栓出血性皮肤病变。超微结构检查显示为微血栓性紫癜。肝素治疗期间凝血因子减少情况有所改善。弥散性血管内凝血的加重是由于妊娠期间的高凝状态,以及“早幼粒细胞纤维蛋白性白血病”尚未明确的病因共同作用所致。